{"id":1540,"date":"2022-08-12T13:31:15","date_gmt":"2022-08-12T19:31:15","guid":{"rendered":"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/?p=1540"},"modified":"2022-09-23T14:43:51","modified_gmt":"2022-09-23T20:43:51","slug":"vaccine-development","status":"publish","type":"post","link":"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/2022\/08\/12\/vaccine-development\/","title":{"rendered":"Vaccine Development"},"content":{"rendered":"\n<div class=\"inherit-container-width wp-block-group has-border-color has-ast-global-color-3-border-color is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:40px;border-style:solid;border-width:6px\"><div class=\"wp-block-group__inner-container\">\n<h4 class=\"wp-block-heading\">Challenges<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<ul class=\"wp-block-list\"><li>Vaccines may have limited efficacy, limited duration of immunity, and potentially severe side effects [1].<\/li><li>Field strains of pathogens evolve quickly and may not be matched by the vaccine strain, resulting in limited efficacy [1].<\/li><li>Some vaccines are not effective on the field strains present in Canadian herds.<\/li><li>There is limited commercial interest in developing vaccines for animal diseases.<\/li><li>Vaccines must be cost-effective and user-friendly to administer.<\/li><\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<ul class=\"wp-block-list\"><li>Some vaccines are not available in Canada. On a world scale, the Canadian market is relatively small and there are relatively large regulatory approval costs associated with distributing products to Canada.<\/li><li>Significant research and development is needed to develop new vaccines, which results in large investments of time and money.<\/li><\/ul>\n\n\n\n<div style=\"height:42px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Further Reading<\/h4>\n\n\n\n<div class=\"wp-block-buttons is-vertical is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-810fbbe0 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ast-global-color-8-color has-pale-cyan-blue-background-color has-text-color has-background\" href=\"https:\/\/veterinaryresearch.biomedcentral.com\/articles\/10.1186\/s13567-018-0560-8\" target=\"_blank\" rel=\"noreferrer noopener\">Vaccines as alternatives to antibiotics for food producing animals<br>Part 1: Challenges and Needs | Veterinary Research<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ast-global-color-8-color has-pale-cyan-blue-background-color has-text-color has-background\" href=\"https:\/\/veterinaryresearch.biomedcentral.com\/articles\/10.1186\/s13567-018-0561-7\" target=\"_blank\" rel=\"noreferrer noopener\">Vaccines as alternatives to antibiotics for food producing animals<br>Part 2: New Approaches and Potential Solutions | Veterinary Research<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:39px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">References<\/h4>\n\n\n\n<p class=\"has-small-font-size\">[1]&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; K. Hoelzer <em>et al.<\/em>, \u2018Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs\u2019, <em>Vet. Res.<\/em>, vol. 49, no. 1, p. 64, Jul. 2018, doi: <a href=\"https:\/\/veterinaryresearch.biomedcentral.com\/articles\/10.1186\/s13567-018-0560-8\" target=\"_blank\" rel=\"noreferrer noopener\">10.1186\/s13567-018-0560-8.<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n\n\n<h5 class=\"has-text-align-center wp-block-heading\">Opportunity Categorization<\/h5>\n\n\n\n<div class=\"wp-block-buttons is-vertical is-content-justification-center is-nowrap is-layout-flex wp-container-core-buttons-is-layout-40a92a1b wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button has-custom-width wp-block-button__width-50\"><a class=\"wp-block-button__link has-ast-global-color-5-color has-ast-global-color-0-background-color has-text-color has-background\" href=\"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/home\/fighting-amr\/immune-support\/\"><strong>Immune Support<\/strong><\/a><\/div>\n\n\n\n<div class=\"wp-block-button has-custom-width wp-block-button__width-50\"><a class=\"wp-block-button__link has-ast-global-color-8-color has-text-color\" href=\"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/home\/fighting-amr\/immune-support\/vaccinations\/\">Vaccinations<\/a><\/div>\n<\/div>\n\n\n\n<div class=\"inherit-container-width wp-block-group is-layout-constrained wp-block-group-is-layout-constrained\"><div class=\"wp-block-group__inner-container\">\n<h5 class=\"has-text-align-center wp-block-heading\">Related Opportunities:<\/h5>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ast-global-color-8-color has-ast-global-color-2-background-color has-text-color has-background\" href=\"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/home\/fighting-amr\/surveillance-and-tracking\/supply-chain-transparency\/\">Supply Chain Transparency<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-ast-global-color-5-color has-ast-global-color-3-background-color has-text-color has-background\" href=\"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/2022\/08\/12\/vaccine-delivery\/\">Vaccine Delivery<\/a><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<div style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Challenges Vaccines may have limited efficacy, limited duration of immunity, and potentially severe side effects [1]. Field strains of pathogens evolve quickly and may not be matched by the vaccine strain, resulting in limited efficacy [1]. Some vaccines are not effective on the field strains present in Canadian herds. There is limited commercial interest in [&hellip;]<\/p>\n","protected":false},"author":441,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ngg_post_thumbnail":0,"footnotes":""},"categories":[14,13,11,18,33,29,20,15,24,21,16],"tags":[37,38],"class_list":["post-1540","post","type-post","status-publish","format-standard","hentry","category-amr-researcher","category-beef-producer","category-entire-value-chain","category-feedlot","category-opportunities","category-policy-maker","category-process","category-product","category-technology-developer","category-user-need","category-veterinarians","tag-existing-solution","tag-optimization-opportunity"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Vaccine Development - Antimicrobial Resistance Opportunity Mapping<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wpsites.ucalgary.ca\/amr-intervention-maps\/2022\/08\/12\/vaccine-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Vaccine Development - Antimicrobial Resistance Opportunity Mapping\" \/>\n<meta property=\"og:description\" content=\"Challenges Vaccines may have limited efficacy, limited duration of immunity, and potentially severe side effects [1]. 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